NCT03704844Unknown不适用
Evaluation of the Renal Congestion, Perfusion and Function Before and After Diuretic Treatment in the ICU
University Hospital, Strasbourg, France3 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2018年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 120
- 试验地点
- 3
- 主要终点
- Effects of diuretics
研究概览
简要总结
Renal congestion is a pathological state that can lead to acute kidney failure. Furosemide is known to lower renal congestion by its diuretic effect.
The aim of this trial is to study the reversibility of kidney congestion under diuretic therapy and assess through echodoppler parameters if it can improve renal perfusion and function in congestive ICU patients.
It could in fine lead to a better identification of patients that could benefit from diuretic therapy in the ICU.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient hospitalized in ICU
- •under furosemide treatment
排除标准
- •participation refusal
- •uncontrolled shock (MAP<65mmHg)
- •abdominal compartment syndrome
- •diuretic administration in the 6 hours prior to inclusion
- •renal replacement therapy or stage 4-5 chronic kidney disease
- •atrial fibrillation
- •no monitoring of CVP / invasive arterial pressure
结局指标
主要结局
Effects of diuretics
时间窗: 24 hours
Evaluation of renal perfusion diuretic treatment by measuring the renal resistance index and the renal venous impedance index.
次要结局
未报告次要终点
研究者
研究点 (3)
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