Evaluation of the Renal Congestion, Perfusion and Function Before and After Diuretic Treatment in the ICU
- Conditions
- Renal Congestion
- Interventions
- Other: non applicable
- Registration Number
- NCT03704844
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
Renal congestion is a pathological state that can lead to acute kidney failure. Furosemide is known to lower renal congestion by its diuretic effect.
The aim of this trial is to study the reversibility of kidney congestion under diuretic therapy and assess through echodoppler parameters if it can improve renal perfusion and function in congestive ICU patients.
It could in fine lead to a better identification of patients that could benefit from diuretic therapy in the ICU.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- patient hospitalized in ICU
- under furosemide treatment
Exclusion Criteria
- participation refusal
- uncontrolled shock (MAP<65mmHg)
- abdominal compartment syndrome
- diuretic administration in the 6 hours prior to inclusion
- renal replacement therapy or stage 4-5 chronic kidney disease
- atrial fibrillation
- no monitoring of CVP / invasive arterial pressure
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients without renal congestion non applicable - Patients with renal congestion non applicable -
- Primary Outcome Measures
Name Time Method Effects of diuretics 24 hours Evaluation of renal perfusion diuretic treatment by measuring the renal resistance index and the renal venous impedance index.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
CHU Amiens-Picardie
🇫🇷Amiens, France
CHU de Dijon
🇫🇷Dijon, France
Les Hôpitaux Universitaires de Strasbourg
🇫🇷Strasbourg, France