Comparing two ways to predict who will survive in the ICU: One uses a scoring system called APACHE IV score, while the other estimates Serum Hepcidin levels through a blood test
Phase 4
- Conditions
- Health Condition 1: 4- Measurement and Monitoring
- Registration Number
- CTRI/2024/05/067373
- Lead Sponsor
- Government Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age more than 18 years,
Below 65 years,
Patient in ICU stay more than 48 hours
Exclusion Criteria
1. Refusal to consent from patient’s relative
2. ICU stay less than 2 days (shift to ward or discharge within 2 days)
3. Burns
4. Head injury
5. Patients receiving chemotherapy/ having malignancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of Acute Physiology and Chronic Health Evaluation IV score and serum hepcidin levels as predictor of mortality in patients admitted to intensive care unitTimepoint: APACHE IV score will be calculated within 24 hours of admission in ICU. <br/ ><br>Serum hepcidin level measured after 48 hours of admission in ICU.
- Secondary Outcome Measures
Name Time Method Correlation of APACHE IV score with development of sepsis and length of stay in ICUTimepoint: APACHE IV score will be calculated within 24 hours of admission in ICU.;Correlation of serum hepcidin levels with development of sepsis and length of stay in ICUTimepoint: Serum hepcidin level will be measured after 48 hours of admission in ICU.;Correlation of SOFA score to predict the development of sepsisTimepoint: SOFA score calculated after 48 hours of admission and will be done every alternate days at a given designated time