Analysis of the differential effects of anti thymocyte globulin (ATG) on lymphocyte subsets in patients with severe aplastic anemia

Withdrawn

• Conditions: 10002086; severe aplastic anemia; acquired aplastic anemia

• Registration Number: NL-OMON42742
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- Age 18 years or older
- Acquired aplastic anemia based on diagnosis criteria of the Dutch Guidelines for diagnosis and treatment of adult aplastic anemia
- Planned treatment with ATG

Exclusion Criteria

- Severe psychological disturbances.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Number and phenotype of circulating lymphocytes before, during and after<br /><br>treatment with ATG</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Persistence and binding capacity of ATG derived antibodies</p><br>