Does diabetic mellitus with cardiac autonomic neuropathy increase incidence of post induction hypotension in elderly patients undergo general anesthesia

• Conditions: DM with cardiac autonomic neuropathy and elderly patient are the risk of intraoperative hypotension.Postinduction hypotension lead to severe complication e.g. .MI, stroke, AKI so anesthesiologist ar; DM, Cardiac autonomic neuropathy, postinduction hypotension, Eldery, General anesthesia

• Registration Number: TCTR20200608005
• Lead Sponsor: HREC Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-08
• Study Completion: 2020-11-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

1. Age >= 65 year-old
2. DM type II
3. Elective surgery under general anesthesia with oroendotracheal tube
4. ASA II-III

Exclusion Criteria

1.ICU care prior to OR
2. On ECMO
3. On vasoactive drug
4. U/D; Coronary artery disease
5. U/D; CVA
6. Cardiac arrhythmia
7. Intubation prior to OR
8. Difficult intubation
9. Plan rapid sequence induction
10. EF < 35%
11. BMI < 16 or > 35
12. Albumin < 2
13. Plan for combine GA and RA

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compare incidence of post induction hypotension in eldery with DM with/without CAN Intraoperative peroid Incidence

Secondary Outcome Measures

Name	Time	Method
Compare probability of vasoactive drug administration of both groups. Intraoperative peroid Incidence,Compare probability of vasoactive drug administration of both groups. Intraoperative peroid Incidence