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Clinical Trials/NCT01907269
NCT01907269
Completed
Not Applicable

Activating Patients to Reduce OsteoPOrosiS

University of Alabama at Birmingham7 sites in 1 country2,684 target enrollmentAugust 2013
ConditionsOsteoporosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoporosis
Sponsor
University of Alabama at Birmingham
Enrollment
2684
Locations
7
Primary Endpoint
Number of Participants That Initiate an Osteoporosis Prescription Medication
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to conduct a randomized trial of a tailored intervention designed to provide personalized feedback regarding patients' risk of subsequent fractures, customized information regarding osteoporosis care, and messaging to activate patients to become more engaged in improving osteoporosis treatment and doctor-patient communication. This novel content will use "story-telling" delivered via the Internet and digital video discs (DVDs). The content will be uniquely tailored to each person based on barriers to care, age and race/ethnicity. We will conduct a controlled, cluster-randomized trial of this intervention to determine differences in post-intervention rates of osteoporosis care between two randomization arms.

We hypothesize that participants randomized to the intervention arm, compared to those randomized to a control arm, will receive more osteoporosis care at 6 months post-intervention, as evidenced by higher rates of: (H1) Prescription osteoporosis therapies, (H2) Non-prescription therapy with calcium and vitamin D, and (H3) Bone mineral density (BMD) testing.

Registry
clinicaltrials.gov
Start Date
August 2013
End Date
November 2016
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kenneth Saag, MD, MSc

Professor of Medicine

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

  • Self-reported history of fracture

Exclusion Criteria

  • Self-reported current prescription osteoporosis treatment

Outcomes

Primary Outcomes

Number of Participants That Initiate an Osteoporosis Prescription Medication

Time Frame: 6 months post-intervention

We will assess the number of participants that self-report the initiation of an osteoporosis prescription medication. It will be assessed using a self-completed survey. Osteoporosis prescription medications that will be assessed include: alendronate, calcitonin, denosumab ibandronate, raloxifene, risedronate, teriparatide, and zoledronic acid. We will not include initiation of estrogen hormone therapies as part of the primary outcome.

Secondary Outcomes

  • Number of Participants Who Reported Use of Calcium and Vitamin D(6 and 18 months post-intervention)
  • Number of Participants Who Reported Receipt of Bone Mineral Density (BMD) Testing(6 and 18 months post-intervention)
  • Number of Participants That Initiate an Osteoporosis Prescription Medication(18 months)

Study Sites (7)

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