Clinical and Radiographic Evaluation of Natural Bovine Bone With Hyaluronic Acid on Osseointegration of Immediate Implant: A Randomized Clinical Study
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Bone density
研究概览
简要总结
the goal of this study is to evaluate the effective of natural bovine bone with hyaluronic acid on osseointegration of immediate implants in single rooted badly decayed maxillary anterior teeth and premolars. the main question it aims to answer is does natural bovine with hyaluronic acid affects osseointegration of immediate implants.
the study compares immediate implants followed by grafting with natural bovine bone with hyaluronic acid to immediate implants without grafting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •medically free patients, good oral hygiene, no periapical lesions around teeth to be extracted
排除标准
- •patients with bone or soft tissue defects, poor oral hygiene, heavy smoking, bruxism, severe periodontal disease
研究组 & 干预措施
control group
control group: 8 immediate implants were inserted in 8 fresh extraction sockets without bone grafting.
干预措施: immediate dental implant (Combination Product)
study group
study group: 8 immediate implants were inserted in 8 fresh extraction sockets followed by grafting with natural bovine bone substitute material with hyaluronic acid
干预措施: immediate dental implant, natural bovine bone substitute material (Combination Product)
结局指标
主要结局
Bone density
时间窗: baseline (immediately) and 6 months
using cone beam CT bone density was measured around the implant in housefield units immediately after implant placement and after 6 months.
implant stability
时间窗: Baseline (immediately) and after 4 months
using Osstell device, implant stability was measured immediately after implant placement and after 4 months
次要结局
- Bone width(Baseline (immediately) and 6 months)
研究者
mohamed wageh foad
principal investigator
Suez Canal University