Hyaluronic Acid Effect on Xenogenic Bone Substitutes Healing During Ridge Preservations: A Radiological and Histomorphometric Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 7
- 试验地点
- 3
- 主要终点
- Radiological assessement of the boe resorption
研究概览
简要总结
The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation.
Following tooth extraction, bone particles are mixed with the hyaluronic acid gel and grafted in the tooth socket. at the implant placement phase, a cone beam computer assisted tomography file is recorded in order to compare it with the baseline and a biopsy to evaluate the histological consequences.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients in need of tooth extraction and willing to receive dental implants in the extraction site
- •Presence of two mono radicular teeth in need of extraction
排除标准
- •Patients with systemic diseases
- •Patients under 8 years and above 60 years.
- •Presence of endodontic or periodontal lesion in the extraction sites
结局指标
主要结局
Radiological assessement of the boe resorption
时间窗: 4 months
the baseline if the CBCT is compared to the 4 months post-op to assess the bone resorption
Histomorphometric analysis
时间窗: 4 months
During implant placement, a bone biopsy is harvested and stained with different colorants to assess microscopically the biological healing
次要结局
未报告次要终点