Automated Pupillometry for the Diagnosis of Horner's Syndrome in Acute Stroke Patients Due to Carotid Artery Dissection
试验速览
- 阶段
- 不适用
- 入组人数
- 135
- 试验地点
- 2
- 主要终点
- Finding of pupillary dilation lag using pupillometry in patients with acute stroke due to carotid artery dissection
研究概览
简要总结
Horner's syndrome (HS) is a result of interruption of the sympathetic innervation to the eye and ocular adnexa, which can occur due to carotid artery dissection (CAD), along which the sympathetic nerve fibers travel to reach the eye. Dissection of the carotid artery is one of the etiologies for ischemic stroke in young patients.
In our current study, we will explore the diagnostic accuracy of automated binocular pupillometry in the diagnosis or HS, and its potential in identifying dissection of the carotid artery in patients of young age who suffer ischemic stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults 60 years of age or younger
- •Acute stroke (less than 72 hours from admission)
- •Informed Consent as documented by signature (Appendix Informed Consent Form)
- •Ability to understand the study information and consent form
排除标准
- •known history of HS
- •Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
- •Medications affecting pupillary response
- •History of ocular surgery affecting the pupil
结局指标
主要结局
Finding of pupillary dilation lag using pupillometry in patients with acute stroke due to carotid artery dissection
时间窗: 1 day of initial visit
次要结局
未报告次要终点
研究者
Konrad Peter Weber
Principal Investigator
University of Zurich