Analgesic Efficacy of Ultrasound-Guided Deep Serratus Anterior Plane Block, Local Wound Infiltration, and Thoracic Paravertebral Block After Uniportal Video-Assisted Thoracic Surgery: A Randomized Trial
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- Time to first analgesic requirement
研究概览
简要总结
Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).
详细描述
Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).
Adequate postoperative pain relief is imperative to hasten functional recovery, accelerate discharge from the hospital, and reduce chronic postsurgical pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for uniportal VATS under general anesthesia, ASA status I-III, aged from 18 to 70 years old of both sex.
排除标准
- •Contraindications to regional block
- •Pregnancy
- •Body mass index (BMI) > 30 Kg/m2
- •Psychiatric diseases
- •Severe renal, liver, or cardiac dysfunction
研究组 & 干预措施
Group I
Patients will receive ultrasound-guided deep serratus anterior plane block.
干预措施: Ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine (Drug)
Group II
Patients will receive local wound infiltration (LWI).
干预措施: Local wound infiltration with isobaric bupivacaine (Drug)
Group III
Patients will receive ultrasound-guided thoracic paravertebral block.
干预措施: Ultrasound-guided thoracic paravertebral block with isobaric bupivacaine (Drug)
结局指标
主要结局
Time to first analgesic requirement
时间窗: 24 hours after surgery
Assessed in minutes
次要结局
- Postoperative pain intensity(24 hours after surgery)
研究者
Seham Mohamed Moeen Ibrahim
Assistant professor of Anesthesia and Intensive Care
Assiut University