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Efficacy and Safety of the Mometasone Nasal Gel in the Treatment of Persistent Allergic Rhinitis

Phase 3
Withdrawn
Conditions
Allergic Rhinitis
Interventions
Registration Number
NCT02953366
Lead Sponsor
EMS
Brief Summary

The purpose of this study is to evaluate the non-inferiority of the clinical efficacy of the mometasone nasal gel in the treatment of allergic rhinitis.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Signed Consent of the patient;
  • Clinical diagnosis of moderate - severe persistent allergic rhinitis according to ARIA classification(Allergic Rhinitis and Its Impact on Asthma);
Exclusion Criteria
  • Patients with any clinically significant disease that in the investigator is opinion can´t participate in the study;
  • Patients with any laboratory finding or image finding that in the investigator is opinion can´t participate in the clinical trial;
  • Patients with history of hypersensitivity to any of the formula compounds;
  • Participation in clinical trial in the year prior to this study;
  • Pregnancy or risk of pregnancy and lactating patients;
  • Patients who were in use of drugs that can interfere with evaluation;
  • Decongestants dependent patients or patients receiving allergen specific immunotherapy;
  • Patients on treatment with monoamine oxidase inhibitors (MAOIs).

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
EMS Mometasone gelEMS Mometasone gelThe patient should administer 1 spray in each nostril once daily.
Mometasone spray nasalMometasone spray nasalThe patient should administer 1 spray in each nostril once daily.
Primary Outcome Measures
NameTimeMethod
Efficacy of allergic rhinitis treatment based proportion of participants who show at least moderate relief.28 days
Secondary Outcome Measures
NameTimeMethod
Safety will be evaluated by the adverse events occurrences28 days
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