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Comparison of a lactose-free medical diet and a lactose-free formula in acute childhood diarrhea

Phase 4
Recruiting
Conditions
acute diarrhea in children.
diarrhea, lactose-free medical formula, children
Registration Number
TCTR20240706013
Lead Sponsor
Thai Otsuka Pharmaceutical Co., Ltd. 
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
44
Inclusion Criteria

1.Patients of both sexes who are at 6-24 months
2.Taking non lactose-free formula milk
3. Admitted at the hospital with watery diarrhea at least 1 time or diarrhea more than 3 times within 1 day but not more than 7 day
4.Obtain inform consent form his/her legal representative

Exclusion Criteria

1. Taking lactose-free formula within 7 days previous enrollment.
2. Sepsis
3. Severe dehydration
4. Having history or diagnosed with Inflammatory bowel disease, necrotizing enterocolitis, intussusception, volvulus, celiac disease, immune deficiency, chronic disease that effect study outcome, advance cancer and terminal disease
6. Taking only breast milk
7. Not able to taking investigated product.
8. Taking prebiotic within 7 days previous enrollment.
9. Taking antibiotic within 7 days previous enrollment.
10. Taking smecta, hidrasec or dehecta within 7 days previous enrollment.
11. Having mucus bloody diarrhea
12. Allergic to cow's milk or components of study formula .
13. Taking other investigated product or stop taking not more than 30 days previous enrollment.
14. Having bacterial infection (except GI system) and taking antibiotic

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diarrheal symptoms (stool characteristics and frequency) Enrollment, discharge the hospital and follow up visit Observation
Secondary Outcome Measures
NameTimeMethod
Body weight Enrollment, discharge the hospital and follow up visit Weighing,Gastrointestinal adverse event During the study Observation,quality of life of subject and their parent End of the study Questioniare,Cost of lactose-free formula in the study End of the study Calculation
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