A pilot study examining the analgesic effect of ascending buprenorphine doses in opioid dependent people

South Eastern Sydney Local Health District0 个研究点目标入组 8 人开始时间: 2014年9月25日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•1.Being at least 18 - 60 years of age
•2.Being of general good medical and psychiatric health
•3.Female participants must not be pregnant or nursing, and must have agreed to use an acceptable method of birth control.
•4.Be stable buprenorphine treatment, including being on a stable dose of buprenorphine (4-16mg/day) at least 10 days.
•5.Be willing to and capable of signing an informed consent.
•6.Primary language spoken is English

•Potential participants must not:
•1.Be dependent on alcohol, benzodiazepines, cannabis or other drugs of abuse that require immediate medical attention or be unsafe in the context of the study.
•2.Be actively involved in another clinical trial.
•3.Have a physiological, neurological or psychiatric illness (e.g. schizophrenia, Raynaud’s disease, urticaria, stroke) that would affect pain responses.
•4.Be currently taking analgesic medication for a painful condition on a regular basis.
•5.Be currently taking a medication known to affect pain response (e.g. antidepressants)
•6.Be taking medications, herbal or vitamin supplements or other dietary supplements (eg grapefruit juice) that may interfere with the metabolism of the study medication.

发起方