Short term effects of exercise training on exercise capacity and quality of life in patients with pulmonary arterial hypertensio

Not Applicable

Recruiting

• Conditions: pulmonary arterial hypertension; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system

• Registration Number: ACTRN12609000502235
• Lead Sponsor: Curtin University of Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Idiopathic or familial PAH
WHO functional class II and III
Medically stable
On PAH-specific medication for at least 3 months prior to enrolment
Able/willing to attend an exercise class and continue with a home exercise program

Exclusion Criteria

PAH associated with connective tissue diseases
Require oxygen therapy
Significant musculoskeletal, neurological or cognitive impairments that limit the ability to perform in a class environment
Involvement in a supervised exercise program within the last 12 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reported number of adverse events. Adverse<br>events may include: (i) incident requiring a medical emergency team call (according to Royal Perth Hospital (RPH) criteria); (ii)<br>exercise-related incident requiring presentation to Emergency Department or General Practitioner; (iii) hospital<br>admission due to PAH or worsening right heart failure;[Throughout study period, if an adverse event occurs];exercise capacity as measured by cardiopulmonary exercise tests - incremental and contant-workload [peak oxygen uptake (VO2), anaerobi threshold (AT), endurance time][Baseline, 12 and 24 weeks];Health related quality of life using the SF36 and Cambridge Pulmonary Hypertension Outcome Review[Baseline, 12 and 24 weeks]