Correlation Analysis Between Corneal Biomechanics and Anterior Segment

Completed

• Conditions: Anterior Sclera Thickness; Ciliary Muscle Thickness; Corneal Biomechanics; CASIA2
• Interventions: Other: Pentacam, Corvis ST and Casia2

• Registration Number: NCT06109636
• Lead Sponsor: Tianjin Eye Hospital

Brief Summary

Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics. Clarify whether aqueous humor displacement, anterior sclera, and ciliary muscles influence the assessment of in vivo corneal biomechanics.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-04
• Status Verified: 2023-10
• Primary Completion: 2023-10-01
• Study Completion: 2023-10-01
• Study First Submitted: 2023-10-21
• Study First Submitted QC: 2023-10-28
• Last Update Submitted: 2023-10-28
• Study First Posted: 2023-10-31
• Last Update Posted: 2023-10-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Best corrected visual acuity (BCVA) ≥ 20/20;
2. No other eye diseases except myopia and astigmatism;
3. The cornea was transparent, and there was no cloud or pannus;

Exclusion Criteria

1. Corneal disease;
2. Ocular trauma;
3. Previous ocular surgery;
4. Any anterior segment diseases except cataract;
5. Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination;
6. Pregnant and lactating women;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Normal group	Pentacam, Corvis ST and Casia2	-

Primary Outcome Measures

Name	Time	Method
scleral and ciliary muscle thickness	one year	The thickness of scleral and ciliary muscle(Casia2, quantitative data through the utilization of its integrated ruler system)
biomechanical parameters	one year	The biomechanical parameters(Corvis ST, exporting the quality-assured csv files to analysis)

Trial Locations

Locations (1)

Tiajin Eye Hospital; 🇨🇳 Tianjin, Tianjin, China