Ocular Findings of Polycystic Ovary Syndrome

Completed

• Conditions: Polycystic Ovary Syndrome
• Interventions: Other: Observation

• Registration Number: NCT03896841
• Lead Sponsor: Istanbul Medeniyet University

Brief Summary

Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy reproductive age female controls.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-03-17
• Primary Completion: 2014-03-20
• Study Completion: 2018-03-30
• Status Verified: 2019-01
• Study First Submitted: 2019-01-13
• Study First Submitted QC: 2019-03-28
• Last Update Submitted: 2019-03-28
• Study First Posted: 2019-04-01
• Last Update Posted: 2019-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 38

Inclusion Criteria

• premenopausal with PCOS

Exclusion Criteria

• patients with external ocular disease other than dry eye complaints,
• use of topical drops that can affect the tear film layer,
• contact lens use histories,
• those who received hormone therapy for 6 months,
• those who have systemic medication or systemic disease that may affect the tear film layer and reproductive physiology,
• previous eye surgeries,
• smokers and alcohol users,
• those having diseases (Cushing's syndrome or androgen-secreting tumors) causing similar clinical findings.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
control subjects	Observation	non-pregnant healthy control subjects
PCOS	Observation	premenopausal patients with PCOS

Primary Outcome Measures

Name	Time	Method
Comparison of the corneal biomechanical parameter results (ocular response analyzer).	1 year	measurement of the corneal hysteresis (CH).
Comparison of the anterior segment parameter results (Pentacam).	1 year	measurement of the central corneal thickness.