Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects

Not Applicable

Completed

Interventions: Procedure: Periosteal pedicle graft
Biological: Bioresorbable collagen membrane

Brief Summary: A clinical and radiographic evaluation of autogenous periosteal pedicle graft in comparison with collagen membrane for management of periodontal intrabony defects.

Detailed Description: Twenty patients suffering from advanced chronic periodontitis were included in this randomized controlled clinical trial. Each subject contributed matched pairs of two- or three-walled intrabony defects. Each pair of periodontal defects were randomly assigned into the experimental group; periosteal pedicle graft guided tissue membrane or the positive control group; bioresorbable collagen guided tissue regeneration membrane. Clinical and radiographic parameters were recorded at baseline and at 6 months postoperatively.

Recruitment & Eligibility

Inclusion Criteria

Severe chronic periodontitis patients with at least two sites with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss 2- or 3-wall intrabony defect depth ranging from 3 to 6 mm as detected in periapical radiographs
The facial surface of teeth adjacent to the interproximal defect should be free of extensive recession and marginal bone loss, with at least a 4 to 5 mm band of keratinized gingiva to allow for periosteal manipulation

Exclusion Criteria

Pregnant women
Subjects had <22 permanent teeth
Having any given systemic disease
Taking any type of medication and/or antibiotic therapy during the 3 months before the study
Received periodontal treatment within the past 12 months
Current or former smokers

Arm && Interventions

Group	Intervention	Description
periosteal pedicle graft	Periosteal pedicle graft	autogenous marginal periosteal pedicle graft harvested by partial thickness periodontal flap.
Bioresorbable collagen membrane	Bioresorbable collagen membrane	Equine Achilles tendon collagen barrier membrane

Primary Outcome Measures

Name	Time	Method
Clinical Attachment Level	Baseline and 6 months	Estimation of clinical attachment level in chronic periodontitis patients at baseline and 6 months after guided tissue regeneration

Secondary Outcome Measures

Name	Time	Method
Pocket Depth	Baseline and 6 months	Estimation of pocket depth in chronic periodontitis patients at baseline and 6 months after guided tissue regeneration
Bone Defect Area	Baseline and 6 months	linear measurements collected from a digital radiography program to estimate percentage of defect fill.