ACTRN12618001858280终止4 期
Randomized Evaluation of Beta Blocker and Angiotensin Converting Enzyme Inhibitor (ACEI) /Angiotensin Receptor Blocker (ARB) Treatment in MINOCA Patients.
适应症
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 71
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Age equal or greater than 18 years.
- •2. A clinical diagnosis of MINOCA, including:
- •a. Acute myocardial infarction – as per the universal myocardial infarction Criteria (Thygesen et al, 2018)
- •b. Non-obstructive coronary arteries – no lesion equal or greater than 50% in the potential infarct-related artery.
- •c. No overt non-ischaemic cause for the acute clinical presentation.
- •3. Left ventricle ejection fraction equal or less than 40% - assessed by echocardiography, MRI or left ventriculography prior to
- •randomisation.
- •4. Written informed consent obtained
排除标准
- •Any condition that may influence the patient's ability to comply with study protocol.
- •2. Pregnancy
- •3. Previous revascularization (CABG or PCI)
- •4. Myocarditis Diagnosis (Cardiac MRI proved myocarditis or a strong clinical suspicion
- •of myocarditis as a cause of the index event)
- •5. Clinical signs of heart failure
- •6. Contraindications for ACEI and ARB
- •7. Contraindications for beta-blockers
- •8. Prior use of ACE-I, ARB, or beta blockers, which must continue as per treating
- •9. New indication for beta-blockers or ACEI/ARB other than as secondary prevention as
- •per treating physician.
- •10. Participation in a trial evaluating a drug known to interact with beta blockers or
研究者
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