The Molecular Basis of Inherited Reproductive Disorders

Recruiting

• Conditions: Reproductive Disorder; Hypogonadotropic Hypogonadism; Kallmann Syndrome; Delayed Puberty

• Registration Number: NCT05971836
• Lead Sponsor: Stephanie B. Seminara, MD

Brief Summary

The goal of this study is to learn more about the genes that control puberty and reproduction in humans.

Detailed Description

All study subjects will undergo the same activities. Subjects will provide up to five tubes of blood for genetic analysis, complete a smell test, and answer questions about their health and family history.

Study Timeline

• Study Start: 2021-01-21
• Study First Submitted: 2023-07-17
• Study First Submitted QC: 2023-07-31
• Study First Posted: 2023-08-02
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-30
• Last Update Posted: 2024-07-31
• Primary Completion: 2026-03
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Genetic variation	Day 1	Identification of one or more genetic variations related to reproductive disorders

Trial Locations

Locations (1)

Massachusetts General Hospital; 🇺🇸 Boston, Massachusetts, United States