Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung Disease in Pediatric:Short and Intermediate Outcomes of Two Different Techniques
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Al-Azhar University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- postoperative bowel function score
Study Overview
Brief Summary
Compare the functional and surgical outcomes of laparoscopic-assisted Swenson-like (LASwL) and laparoscopic-assisted Soave (LASo) pull through in children with HD.
Detailed Description
A prospective, randomized study was conducted involving 80 patients diagnosed with HD at Al-Azhar University Hospitals over a 48-month period from September 2020 to August 2024. Participants were randomly allocated to the LASwL (Group A) or LASo (Group B). The primary outcome was the postoperative bowel function score. Secondary outcomes included operative time, blood loss, duration of hospital stay, and incidence of postoperative Hirschsprung-associated enterocolitis (HAEC).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Care Provider)
Eligibility Criteria
- Ages
- 1 Month to 14 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •infants and children diagnosed with Hirschsprung's disease (HD) at the Department of Pediatric Surgery, Al-Azhar University Hospitals, from September 2020 to August 2024
Exclusion Criteria
- •Patients with ultrashort or total colonic aganglionosis and those who had previously undergone pull-through procedures
Arms & Interventions
Group B
20 patients with HD
Intervention: laparoscopic-assisted Soave (LASo) (Procedure)
Group A
20 patients with HD
Intervention: laparoscopic-assisted Swenson-like (LASwL) (Procedure)
Outcomes
Primary Outcomes
postoperative bowel function score
Time Frame: 2 years
This assessment evaluated the ability to hold back defecation, the ability to feel or report the urge to defecate, the frequency of defecation, soiling accidents, constipation, and social issues. Most items are scored on a 0-3 scale, while defecation frequency is scored 1-2, resulting in a maximum total score of 20. A higher score indicates better bowel function, with Scores ranged from 17-20 (excellent), 12-16 (good), 9-11 (fair), and less than 8 (poor)
Secondary Outcomes
No secondary outcomes reported
Investigators
Mohamed Abdelmaboud
assistant professor
Al-Azhar University