Preoperative risk stratification of patients with Aortic Stenosis

Recruiting

• Conditions: Aortic Valve Stenosis; C14.280.484.048

• Registration Number: RBR-7k48gfd
• Lead Sponsor: Hospital das Clínicas da Faculdade de Medicina da USP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-12-11
• Last Update Posted: 19 December 2023
• Study Completion: 2026-08-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Severe Aortic Stenosis undergoing valve replacement surgery; age over 18 years; male and female genders

Exclusion Criteria

Severe aortic insufficiency; severe primary valvular heart disease; heart failure of non-valvular etiology; primary cardiomyopathies; severe obstructive pulmonary disease; endocarditis; three-vessel coronary disease; main stem lesion; previous cardiac surgery;active endocarditis

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Test whether the new stratification predicts the primary composite outcome: all-cause mortality and hospital readmission at 24 months of follow-up after conventional aortic valve replacement surgery in patients with severe aortic stenosis.

Secondary Outcome Measures

Name	Time	Method
Investigate whether there are other predictive factors for the composite outcome of all-cause mortality and in-hospital readmission during the same follow-up period.;Investigate the prevalence of isolated outcomes (death from all causes and hospital readmission) within the same follow-up period.;Test whether the new stratification predicts the secondary outcome of mortality from cardiovascular causes in the same follow-up period.