Major depression in Borderline Personality disorder: A distinct clinical presentation?

Not Applicable

• Conditions: Health Condition 1: - Health Condition 2: F603- Borderline personality disorderHealth Condition 3: F30-F39- Mood [affective] disorders

• Registration Number: CTRI/2023/06/053617
• Lead Sponsor: Department of Psychiatry

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

GROUP A

1.Diagnosis of Borderline Personality disorder as per DSM-5.

2.Diagnosis of Major depressive disorder as per DSM-5.

3.Age between 18-35yrs

4.Written informed consent for study

GROUP B

1.Diagnosis of Major depressive disorder as per DSM-5.

2.Age between 18-35 years.

3.Written informed consent.

Exclusion Criteria

Group A

1.Diagnosis other than Major depressive disorder and/or Borderline personality disorder as per DSM-5 criteria.

2.Diagnosis of substance use-disorder except caffeine and/or Nicotine use disorder as per DSM-5

3.Diagnosis of medical disorder causing/mimicking depression

Group B

1.Diagnosis other than Major depressive disorder as per DSM-5.

2.Diagnosis of substance-use disorder except caffeine and/or Nicotine-use disorder as per DSM-5.

3.Diagnosis of medical disorder causing/mimicking depression.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of Clinical profile of Major depressive disorder in patients with Borderline personality disorder and without Borderline personality disorder.Timepoint: BASELINE

Secondary Outcome Measures

Name	Time	Method
Anxiety symptoms in the two groups (Hamilton anxiety rating scale(Clinician rated)-CROSS SECTIONAL)Timepoint: BASELINE;Core-features of Major depressive disorder in the two groups ( Using Inventory of depressive symptomatology (IDS-30-Clinician rated) CROSS-SECTIONALTimepoint: BASELINE;Psychomotor functioning-Non-interactiveness, retardation and agitation (Using CORE assessment for psychomotor change scale(Clinician rated)-CROSS-SECTIONALTimepoint: BASELINE;Self-harm behavior in the two groups ( Using Self-harm inventory self-rated scale-CROSS SECTIONAL)Timepoint: BASELINE;Somatic symptoms in the two groups (Somatoform disorders symptoms checklist <br/ ><br>CROSS-SECTIONALTimepoint: BASELINE;Suicidality in the two groups (Columbia suicide severity rating scale CROSS SECTIONAL)Timepoint: BASELINE