NCT01602640已完成不适用
Sedation and Analgesia in Intensive Care: Comparison of Morphine and Fentanyl/Midazolam
Clínica de Los Andes IPS1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2009年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Time from sedation discontinuation to first T-Tube time from sedation
研究概览
简要总结
Hypothesis: Morphine infusion decreases time to mechanical ventilation weaning and extubation, as compared to the combination of fentanyl and midazolam in critically-ill patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults admitted to ICU requiring mechanical ventilation Informed consent
排除标准
- •Less than 18 years old
- •Consent denial
研究组 & 干预措施
Morphine
Experimental
干预措施: Morphine infusion (Drug)
Fentanyl and Midazolam
Active Comparator
Control
干预措施: Fentanyl and Midazolam infusion (Drug)
结局指标
主要结局
Time from sedation discontinuation to first T-Tube time from sedation
时间窗: 12-120 hours
次要结局
- Time from sedation discontinuation to extubation time from sedation(12-180 hours)
研究者
EFRAIN RIVEROS
Principal investigator
Clínica de Los Andes IPS
研究点 (1)
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