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Clinical Trials/NCT01602640
NCT01602640
Completed
Not Applicable

Sedation and Analgesia in Intensive Care: Comparison of Morphine and Fentanyl/Midazolam

Clínica de Los Andes IPS1 site in 1 country90 target enrollmentJanuary 2009
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ConditionsRespiratory Failure
InterventionsMorphine infusionFentanyl and Midazolam infusion
DrugsMorphine infusionFentanyl and Midazolam infusion

Overview

Phase
Not Applicable
Intervention
Morphine infusion
Conditions
Respiratory Failure
Sponsor
Clínica de Los Andes IPS
Enrollment
90
Locations
1
Primary Endpoint
Time from sedation discontinuation to first T-Tube time from sedation
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

Hypothesis: Morphine infusion decreases time to mechanical ventilation weaning and extubation, as compared to the combination of fentanyl and midazolam in critically-ill patients.

Registry
clinicaltrials.gov
Start Date
January 2009
End Date
March 2012
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Clínica de Los Andes IPS
Responsible Party
Principal Investigator
Principal Investigator

EFRAIN RIVEROS

Principal investigator

Clínica de Los Andes IPS

Eligibility Criteria

Inclusion Criteria

  • •Adults admitted to ICU requiring mechanical ventilation Informed consent

Exclusion Criteria

  • •Less than 18 years old
  • •Consent denial

Arms & Interventions

Morphine

Intervention: Morphine infusion

Fentanyl and Midazolam

Control

Intervention: Fentanyl and Midazolam infusion

Outcomes

Primary Outcomes

Time from sedation discontinuation to first T-Tube time from sedation

Time Frame: 12-120 hours

Secondary Outcomes

  • Time from sedation discontinuation to extubation time from sedation(12-180 hours)

Study Sites (1)

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