Fecal Microbiota Transplantation in Patients With Irritable Bowel Syndrome

Örebro University, Sweden1 site in 1 country17 target enrollmentSeptember 2013

ConditionsIrritable Bowel Syndrome (IBS)

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Irritable Bowel Syndrome (IBS)
Sponsor: Örebro University, Sweden
Enrollment: 17
Locations: 1
Primary Endpoint: Effect of fecal microbiota transplantation on the symptoms of IBS patients using the IBS version of the gastrointestinal symptom rating scale (GSRS-IBS)
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate the effect of fecal microbiota transplantation (FMT) on the symptoms of irritable bowel syndrome (IBS) patients.

Registry

clinicaltrials.gov

Start Date

September 2013

End Date

June 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Örebro University, Sweden

Responsible Party

Principal Investigator

Robert Brummer

MD, PhD

Örebro University, Sweden

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Effect of fecal microbiota transplantation on the symptoms of IBS patients using the IBS version of the gastrointestinal symptom rating scale (GSRS-IBS)

Time Frame: 6 months

Secondary Outcomes

Effect of fecal microbiota transplantation on the symptoms of IBS patients using the IBS - severity scoring system (IBS-SSS)(6 months)
Effect of fecal microbiota transplantation on the general health of IBS patients using the SF-36 survey(6 months)
Effect of fecal transplantation on IBS patients' composition of mucosal microbiota (HITChip analysis)(2 months)
Effect of fecal transplantation on IBS patients' mucosal immune cell composition (lymphocyte fingerprinting using flow cytometry)(2 months)
Effect of fecal microbiota transplantation on the symptoms of IBS patients using the health-related quality of life questionnaire for IBS patients (IBS-QOL)(6 months)
Effect of fecal microbiota transplantation on the symptoms of IBS patients using the hospital and anxiety depression scale (HADS)(6 months)
Effect of fecal transplantation on IBS patients' visceral perception (Pain scores on the visual analogue scale during barostat procedure)(2 months)
Effect of fecal transplantation on IBS patients' composition of fecal microbiota (HITChip analysis)(6 months)