Progesterone Supplementation in Threatened Abortion
Phase 4
Completed
- Conditions
- Threatened AbortionProgesterone Resistance
- Interventions
- Drug: Placebos
- Registration Number
- NCT03930212
- Lead Sponsor
- Tanta University
- Brief Summary
To decide whether progesterone supplementation in threatened abortion is a sound practice.
- Detailed Description
This study was conducted at Obstetrics and Gynecology Department, Tanta University in the period from January 2018 to December 2018. Patients: Eligible patients (n=190) were randomly allocated into 2 groups; study group who will receive progesterone supplementation (Prog.group) and control group who will receive no treatment (place.group).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 190
Inclusion Criteria
- threatened abortion diagnosed by history and ultrasound examination
- singleton
- viable fetus
- gestational age < 20 weeks
- closed normal length cervix.
Exclusion Criteria
- short cervix <2 cm Multiple pregnancy
- dead fetus
- open cervix ≥ 2cm
- history of cervical surgery
- refusal to participate.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control group Placebos received placebo suppositories rectally once daily. Progesterone Progesterone received rectal progesterone suppositories 400 mg once daily
- Primary Outcome Measures
Name Time Method relief of pain 3 weeks questionnaire fulfilled by patient with yes or no questions
Stoppage of bleeding 3 weeks Cessation of bleeding
completion of pregnancy beyond 20 weeks 12 weeks passing the age 20 weeks
- Secondary Outcome Measures
Name Time Method abortion less than 20 weeks. 12 weeks Abortion
Trial Locations
- Locations (1)
Ayman Shehata Dawood
🇪🇬Tanta, Egypt