MedPath

To study the effect ofnimbatiktam and lajjalu keram gel in the management of psoriasis

Phase 2
Conditions
Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
Registration Number
CTRI/2020/02/023638
Lead Sponsor
Central Council for Research in Ayurvedic Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients of either sex with age between 18 and 60 years.

2. Known cases of psoriasis, without psoriatic arthropathy, Exhibiting psoriatic triad â??

a. Bright pink or red lesions with pronounced edges, covered with silvery white scales,

the scales can be easily separated from the lesion.

b. Under the scales there appears a pinkish moist tender skin.

c. With the scraping of the moist skin there appear tiny blood droplets (Auspitzâ??s sign)

3. Patients suffering from psoriasis with less than 50 % of the body surface involvement.

4. Disease duration between 3 months to 5 years.

5. V.D.R.L./ HIV/Hepatitis negative.

6. Positive histopathological finding.(Skin-biopsy)

7. Willing to participate in the study

Exclusion Criteria

1. Generalized skin lesions, Herpes simplex, Herpes zoster, Scabies, Acne, Urticaria, and

Immunological mediated skin diseases like Pempigus vulgaris, Dermatitis, herpetiformis,

Guttate, Pustular, Lupus erythematous, Psoriatic arthropathy etc.

2. Patients with poorly controlled Hypertension (Blood pressure more than 160/100mm of

Hg).

3. Pregnant or lactating woman.

4. Patient with uncontrolled Diabetes Mellitus (Blood sugar fasting more than 250 mg/dl).

5. Patient suffering from major systemic illness necessitating long term drug treatment

(Rheumatoid arthritis, Tuberculosis, Psycho - Neuro-endocrinal disorders, etc.).

6. Patients on medication with corticosteroids, phototherapy, biologics, antidepressants any

other drugs that may have an influence on the outcome of the study.

7. Patients with concurrent serious Hepatic Dysfunction (defined as AST and/or ALT >3

times of the upper normal limit) or Renal Dysfunction (defined as S. creatinine > 1.4

mg/dl) or uncontrolled Pulmonary Dysfunction (asthmatic and COPD patients) or AIDS or

STD or other concurrent severe disease.

8. Alcoholics and/or drug abusers.

9. H/o hypersensitivity to the trial drug or any of their ingredients.

10. Patients who have completed participation in any other clinical trial during the past six

months.

11. Any other condition which the Investigator thinks may jeopardize the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath