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Portal Vein Flow Velocity as a Screening Tool for Oesophageal Varices in Cirrhotic Patients

Recruiting
Conditions
Cirrhosis Portal
Registration Number
NCT05228509
Lead Sponsor
Peter atef
Brief Summary

Portal vein flow velocity as screening tool for prediction of oesophageal varices in cirrhotic patient without upper endoscopy

Detailed Description

Portal vein flow velocity as screening tool for prediction of oesophageal varices in cirrhotic patient without upper endoscopy with its high cost \& complications Using portal vein flow velocity and the relation between it \& presence of oesophageal varices in cirrhotic patient \& its efficacy as a primary tool for these cases

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
75
Inclusion Criteria
  • cirrhotic patients with oesophageal varices
  • cirrhotic patients without oesophageal varices
Exclusion Criteria
  • Patients with hepato-cellular carcinomas [HCCs], portal vein thrombosis, hepatic encephalopathy.
  • Patients with positive HCV antibody, but without liver cirrhosis diagnostic criteria

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Using upper GIT endoscopy to detect the presence or absence of oesophageal varices3 years

Non-invasive screening tool for esophageal varices:

Aspartate aminotransferase-to-platelet ratio index (APRI) ... Doppler ultrasound of portal system Elastography both of liver and spleen... -Research outcome measures:

a. Primary (main): Using upper GIT endoscopy to detect the presence or absence of oesophageal varices, and to detect the best and most available non- invasive predictor for it.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

43

🇪🇬

Assiut, Manfalout, Egypt

Egypt .assiut.manfalout

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Assiut, Manfalout, Egypt

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