Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing

Not Applicable

Recruiting

• Conditions: Outbreaks

• Registration Number: NCT06660433
• Lead Sponsor: Michael Garron Hospital

Brief Summary

Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with delays leading to missed opportunities to implement virus-specific control measures to interrupt transmission resulting in larger outbreaks. Use of a point-of-care testing platform is a potential solution that provides faster results, but it is uncertain whether this translates into benefits for long-term care residents. This trial aims to assess whether rapid test results for respiratory pathogens (Influenza, COVID-19 and Respiratory Syncytial Virus) can impact the number and size of respiratory virus outbreaks in long-term care homes.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-10-24
• Study First Submitted QC: 2024-10-24
• Study First Posted: 2024-10-28
• Status Verified: 2024-11
• Study Start: 2024-11-11
• Last Update Submitted: 2024-11-25
• Last Update Posted: 2024-11-27
• Primary Completion: 2025-04-30
• Study Completion: 2025-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Long-term care facility engaged with an Ontario Health Team overseen by Sunnybrook Health Science Centre, Michael Garron Hospital or Humber River Health

Exclusion Criteria

• No signed statement of agreement for study participation
• Pre-existing use of a point-of-care testing platform

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Number of long-term care residents infected with COVID-19, Influenza, or RSV	7 months	The number of long-term care residents who contract Influenza, COVID-19 or RSV separated into the number of residents infected after an introduction is identified and the size of an outbreak of each virus.

Secondary Outcome Measures

Name	Time	Method
The number of outbreaks of Influenza, COVID-19 or RSV	7 months	The number of Influenza, COVID-19 or RSV outbreaks as declared by the local Public Health Unit
The number of long-term care residents infected during an outbreak of Influenza, COVID-19 or RSV	28 days	The number of long-term care residents with a confirmed or suspected Influenza, COVID-19 or RSV infection during each outbreak as tracked by the local Public Health Unit
Frequency of hospital transfers for long-term care residents infected with Influenza, COVID-19 or RSV	14 days	The number of hospital transfers for long-term care residents with Influenza, COVID-19 or RSV
Number of deaths in long-term care residents infected with Influenza, COVID-19 or RSV	28 days	The number of long-term care residents who die following an infection with Influenza, COVID-19 or RSV
Duration of outbreaks in of Influenza, COVID-19 or RSV in long-term care facilities	60 days	The total duration of an outbreak of Influenza, COVID-19 or RSV as declared by the local Public Health Unit
Secondary attack rate of high-risk exposures to each long-term care resident with Influenza, COVID-19 or RSV infection	28 days	The proportion of identified high risk contacts of an infected long-term care resident with Influenza, COVID-19 or RSV infection

Trial Locations

Locations (2)

Michael Garron Hospital; 🇨🇦 Toronto, Ontario, Canada

Sunnybrook Health Sciences Centre; 🇨🇦 Toronto, Ontario, Canada