Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly: the CORE Trial in Response to the Pandemic
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- Université de Sherbrooke
- Enrollment
- 124
- Locations
- 2
- Primary Endpoint
- Length of stay
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of hospital stays (LOS), specific data for COVID-19 are lacking. Hence, in response to the current pandemic, we propose to implement and assess the impact of an early standardized multidisciplinary rehabilitation program tailored to frail older adults on 1) LOS, 2) post-discharge destination, 3) prognostic index and 4) functional capacity.
With a pragmatic multicenter controlled study, the COvid Rehabilitation Program for the Elderly (CORE) trial will allow to measure the effectiveness of a multidisciplinary program to minimize the effects of hospitalization and provide the required tools to rapidly implement an innovative strategy of care for older adults. Indeed, based on the results of this study, and with the support of scientific and professional organizations, a standardized program tailored to older adults with COVID-19 will be disseminated in Canada for all medical units dedicated to the management of the disease. Because of its pragmatic approach, this study will provide a sustainable multidisciplinary intervention that can be quickly implemented in any Canadian (or abroad) COVID-19 medical unit. Finally, given that COVID-19 is the third coronavirus infection in the last 20 years, the expected results will provide guidelines, with decision tree algorithms, for implementation should another coronavirus or for that matter, any other such type of infection that surface in the future.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with medical clearance (physical deconditioning; hemodynamically stable; oxygen therapy by nasal cannula \< 4 L/min for saturation \> 92%; resting respiratory rate \< 24; and heart rate between 50 and 120 beats per minute). Controls were paired with those of the CORE program according to age, sex and pre-admission origin
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Length of stay
Time Frame: 1 day after discharge
Length of stay in COVID and subacute unit (days)
Secondary Outcomes
- Post-discharge destination(1 day after discharge)
- Readmission rate 30 days after discharge(30 days after discharge)
- Change in patient prognosis(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))
- Change in functional capacity (lower limb function)(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))
- Change in functional capacity (handgrip strength)(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))