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临床试验/NCT04771052
NCT04771052已完成不适用

Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly: the CORE Trial in Response to the Pandemic

Université de Sherbrooke2 个研究点 分布在 1 个国家目标入组 124 人开始时间: 2020年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
124
试验地点
2
主要终点
Length of stay

研究概览

简要总结

Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of hospital stays (LOS), specific data for COVID-19 are lacking. Hence, in response to the current pandemic, we propose to implement and assess the impact of an early standardized multidisciplinary rehabilitation program tailored to frail older adults on 1) LOS, 2) post-discharge destination, 3) prognostic index and 4) functional capacity.

With a pragmatic multicenter controlled study, the COvid Rehabilitation Program for the Elderly (CORE) trial will allow to measure the effectiveness of a multidisciplinary program to minimize the effects of hospitalization and provide the required tools to rapidly implement an innovative strategy of care for older adults. Indeed, based on the results of this study, and with the support of scientific and professional organizations, a standardized program tailored to older adults with COVID-19 will be disseminated in Canada for all medical units dedicated to the management of the disease. Because of its pragmatic approach, this study will provide a sustainable multidisciplinary intervention that can be quickly implemented in any Canadian (or abroad) COVID-19 medical unit. Finally, given that COVID-19 is the third coronavirus infection in the last 20 years, the expected results will provide guidelines, with decision tree algorithms, for implementation should another coronavirus or for that matter, any other such type of infection that surface in the future.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with medical clearance (physical deconditioning; hemodynamically stable; oxygen therapy by nasal cannula < 4 L/min for saturation > 92%; resting respiratory rate < 24; and heart rate between 50 and 120 beats per minute). Controls were paired with those of the CORE program according to age, sex and pre-admission origin

排除标准

  • 未提供

结局指标

主要结局

Length of stay

时间窗: 1 day after discharge

Length of stay in COVID and subacute unit (days)

次要结局

  • Post-discharge destination(1 day after discharge)
  • Readmission rate 30 days after discharge(30 days after discharge)
  • Change in patient prognosis(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))
  • Change in functional capacity (lower limb function)(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))
  • Change in functional capacity (handgrip strength)(At baseline (± 2 days after admission in the COVID-19 unit) and before discharge (± 3 days))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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