Early Risk Stratification of Patient Hospitalized for SARS-CoV2 Infection: Critical COVID-19 France CCF
- Conditions
- Infection ViralInfection, HospitalCOVID
- Registration Number
- NCT04344327
- Lead Sponsor
- French Cardiology Society
- Brief Summary
The COVID-19 pandemic of SARS CoV2 (Severe Acute Respiratory Syndrome, COVID-19) infection, which is currently evolving in France, raises many questions about the clinical and biological profile of infected hospitalized patients. If certain biological factors like troponin, BNP (Brain Natriuretic Peptid), or clinical factors like cardiovascular history or oncological history are associated with a worse prognosis, available data comes from studies in Asia for the majority, or including a limited number of patients. Patient stratification remains a major issue for patient sorting and early referral of patients.
- Detailed Description
This study is observational, multicenter and retrospective, and is conducted in hospitals in France.
Clinical data relating to history, comorbidities, risk factors, previous treatments, treatments during the hospitalization and treatments at the discharge from hospital, clinical parameters, biological and ultrasound cardiological data, procedures and events during hospitalization will be recorded, in order to identify the early predictors of clinical worsening in patients hospitalized for COVID-19 in cardiology or conventional medicine department.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2878
- Patients hospitalized in cardiology unit or medicine conventional sector with diagnosis of COVID-19 (positive PCR (Polymerase Chain Reaction) or diagnosis presumed by the clinical and radiographic picture)
- Minors
- Pregnant women
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Death rate Through study completion, an average of 4 weeks Analysis of all-cause death in relation with clinical patient profile
Ventilation analysis Through study completion, an average of 4 weeks Type of ventilation procedures needed during the hospitalization (Orotracheal intubation for mechanical ventilation or Non-invasive ventilation or 29/5000 high flow oxygen therapy - Optiflow) in relation with clinical patient profile
Transfer to intensive care unit Through study completion, an average of 4 weeks Correlation between clinical patient profile and transfer need to intensive care unit
- Secondary Outcome Measures
Name Time Method Construction of a predictive score for COVID-19 severe form Through study completion, an average of 4 weeks Description of clinical and biological patient profile leading to a worse prognosis
Related Research Topics
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Trial Locations
- Locations (23)
CHU d'Amiens
🇫🇷Amiens, France
CHU Annecy
🇫🇷Annecy, France
CHU de Bordeaux
🇫🇷Bordeaux, France
CHU de Caen
🇫🇷Caen, France
Cotentin hospital
🇫🇷Cherbourg, France
CHU Dijon
🇫🇷Dijon, France
Elbeuf Louviers Val de Reuil
🇫🇷Elbeuf, France
CHU de Fréjus / Saint-Raphael
🇫🇷Fréjus, France
Lille Catholic Institute Hospital Group, Lille
🇫🇷Lille, France
CHU de Lyon
🇫🇷Lyon, France
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