The impact of physical activity on breast cancer survivors

Not Applicable

• Conditions: The impact of physical activity on health in breast cancer survivors; Not Applicable

• Registration Number: ISRCTN45696887
• Lead Sponsor: Akademii Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-04
• Last Update Posted: 17 January 2022
• Study Completion: 2022-09-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 180

Inclusion Criteria

1. Patient's written consent to participate in the study
2. Age 30 - 70 years
3. First treatment of non-disseminated breast cancer
4. 0 - III degree of cancer
5. Overweight and obesity (BMI >25 kg/m²)
4. Treatment of breast cancer (mastectomy and minimally invasive surgery)
5. Adjuvant treatment (chemotherapy, immunotherapy, hormone therapy, radiotherapy) based on the medical indications
6. Completed radiotherapy and chemotherapy from 4 weeks to 6 months before the study start
7. No physical training for more than 60 minutes a week before the start of the study
8. Hormone therapy and/or immunotherapy,
9. Minimum of 5 years from the end of treatment for another malignant tumor

Exclusion Criteria

1. Contraindications to physical training at the intensity specified in the study
2. Refusal to participate in the study
3. Co-morbidities disrupting the body’s balance including diseases of the nervous system, balance organ, eyes, muscles and joints (amputations, unequal limb length >2 cm, joint stiffness and limited range of movement in lower extremities above 15 degrees)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Quality of life assessed with the EORTC QLQ – C30 - Quality of Life Questionnaire of Cancer Patients at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 2. Quality of life assessed with the EORTC QLQ – BR 23 - Quality of Life Questionnaire for Breast Cancers at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 3. Postural stability assessed by AMTI's AccuGait Optimized™ multi-axis force platform tests at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 4. Postural stability assessed by Timed Up and Go test (TUG) at baseline, after finishing 6-week physical training and 6 weeks after treatment<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Physical activity level assessed by Physical Activity Questionnaire (IPAQ) questionnaire at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 2. Fatigue level assessed by Brief Fatigue Inventory (BFI) at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 3. Locomotor function assessed by 4-Meter Gait Speed test (4MGS) at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 4. Pain is measured using a visual analogue scale (VAS) at baseline, after finishing 6-week physical training and 6 weeks after treatment<br> 5. Fall risk is measured using the Falls Efficacy Scale-International (FES-I) at baseline, after finishing 6-week physical training and 6 weeks after treatment<br>