Epidemiology and Management of invasive infections among people who Use drugs (EMU)

Not Applicable

Recruiting

• Conditions: Injecting drug use; Infective endocarditis; Osteomyelitis; Bacteraemia; Epidural abscess; Infection - Studies of infection and infectious agents; Mental Health - Addiction

• Registration Number: ACTRN12622001173785
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-08-30
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 146

Inclusion Criteria

Subjects will be eligible for this study if they:
*Are adult patients aged at least 18 years
*Have a history of current intravenous drug use (IDU). Current IDU defined as use within six months prior to admission.
*Are admitted to hospital for management of invasive bacterial or fungal infection (proven or presumed).

Invasive infections are defined by treating physician diagnosis (proven or presumed) of the following infections:
*Infective endocarditis
*Epidural abscess
*Bone and join infection (including osteomyelitis, septic arthritis, or prosthetic joint infection)
*Other deep abscess (excluding acute bacterial skin and skin structure infections (ABSSSI) but including soft tissue such as muscle/ lung/ liver/ spleen/ cerebral with no evidence of infective endocarditis)
*Bacteraemia or candidaemia not otherwise specified (excluding infective endocarditis)

Exclusion Criteria

EMU-Audit:
*Patients with acute bacterial skin and skin structure infections (ABSSSI) only and no evidence of invasive infection
*Patients admitted for management of viral infection only (HAV/ HBV/ HCV/ HIV) and no evidence of bacterial or fungal infection
*Patients admitted for management of viral or bacterial meningitis only with no evidence of above invasive infections
*Patients admitted for a reason unrelated to an acute infection (such as trauma), who subsequently develop an invasive infection

EMU-Cohort:
As per exclusion criteria for EMU-Audit patients AND
*Refusal to participate
*Patient unable to give informed consent including if not fluent in English to be able to understand the PICF and participate in the consent process
*No access to landline or mobile telephone for follow up

Study & Design

• Study Type: Observational
• Study Design: Not specified