Alteplase v.s. Trisodium Citrate and Infection and Obstruction Incidence of Permanent Tunneled Dialysis Catheters

Phase 4

Recruiting

• Conditions: The incidence of infection and obstruction of permanent tunneled dialysis catheters; infection in dialysis; Renal and Urogenital - Kidney disease

• Registration Number: ACTRN12612000152820
• Lead Sponsor: Pavlina Richtrova, MD, PhD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-02-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients with end stage kidney disease and newly inserted permanent tunneled dialysis catheter. Dialysis prescription = 3 times a week. Agreement with the trial participation.

Exclusion Criteria

- anticoagulation treatment INR more than 1.4
- platelets count less than 60x109/l
- catheter insertion in vena cava inferior region (femoral vein)
- catheter insertion by a guide-wire exchange procedure
- active pericarditis with pericardial effusion
- known allergy or intolerance to alteplase or trisodium
- citrate pregnancy or breast-feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified