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CHUGAI PHARMACEUTICAL CO., LTD.

CHUGAI PHARMACEUTICAL CO., LTD. logo
🇯🇵Japan
Ownership
Public, Subsidiary
Established
1925-03-10
Employees
7.6K
Market Cap
$83.6B
Website
http://www.chugai-pharm.co.jp

Clinical Trials

635

Active:23
Completed:316

Trial Phases

5 Phases

Phase 1:136
Phase 2:77
Phase 3:246
+2 more phases

Drug Approvals

9

NMPA:9

Drug Approvals

Nicorandil for Injection

Product Name
喜格迈/Sigmart
Approval Number
国药准字HJ20240010
Approval Date
Apr 24, 2024
NMPA

Nicorandil Tablets

Product Name
喜格迈
Approval Number
国药准字HJ20160540
Approval Date
Oct 10, 2021
NMPA

Nicorandil Tablets

Product Name
喜格迈
Approval Number
国药准字HJ20181010
Approval Date
Oct 10, 2021
NMPA

Nicorandil Tablets

Product Name
喜格迈
Approval Number
国药准字HJ20160539
Approval Date
Oct 10, 2021
NMPA

Eldecalcitol Soft Capsules

Product Name
艾地骨化醇软胶囊
Approval Number
国药准字HJ20200058
Approval Date
Dec 11, 2020
NMPA

Eldecalcitol Soft Capsules

Product Name
艾地骨化醇软胶囊
Approval Number
国药准字HJ20200057
Approval Date
Dec 11, 2020
NMPA

Recombinant Human Granulocyte Colony-stimulating Factor for Injection(CHO cell)

Product Name
格拉诺赛特
Approval Number
S20140020
Approval Date
Sep 16, 2019
NMPA

Recombinant Human Granulocyte Colony-stimulating Factor for Injection(CHO cell)

Product Name
格拉诺赛特
Approval Number
S20140021
Approval Date
Sep 16, 2019
NMPA

Recombinant Human Granulocyte Colony-stimulating Factor for Injection(CHO cell)

Product Name
格拉诺赛特
Approval Number
S20140019
Approval Date
Sep 11, 2019
NMPA

Clinical Trials

Distribution across different clinical trial phases (579 trials with phase data)• Click on a phase to view related trials

Phase 3
246 (42.5%)
Phase 1
136 (23.5%)
Not Applicable
84 (14.5%)
Phase 2
77 (13.3%)
Phase 4
23 (4.0%)
phase_1_2
9 (1.6%)
phase_2_3
4 (0.7%)

A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER

Not Applicable
Not yet recruiting
Conditions
Extensive Stage Small Cell Lung Cancer
Interventions
First Posted Date
2025-08-06
Last Posted Date
2025-08-06
Lead Sponsor
Chugai Pharmaceutical
Target Recruit Count
122
Registration Number
NCT07107490
Locations
🇯🇵

National Cancer Center Hospital East, Kashiwa, Chiba, Japan

Study of AUBE00 in Patients With Solid Tumors

Phase 1
Recruiting
Conditions
Solid Tumors
Interventions
Drug: AUBE00
First Posted Date
2025-06-22
Last Posted Date
2025-08-05
Lead Sponsor
Chugai Pharmaceutical
Target Recruit Count
100
Registration Number
NCT07030959
Locations
🇺🇸

South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids, Michigan, United States

🇺🇸

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

🇯🇵

National Cancer Center Hospital East, Kashiwa, Chiba, Japan

and more 1 locations

Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)

Phase 1
Conditions
Antiphospholipid Syndrome (APS)
Bullous Pemphigoid (BP)
Dermatomyositis (DM)
Immune-mediated Necrotizing Myopathy (IMNM)
Behçet's Syndrome (BS)
Immune Thrombocytopenia (ITP)
Interventions
First Posted Date
2024-12-09
Last Posted Date
2025-05-31
Lead Sponsor
Chugai Pharmaceutical
Target Recruit Count
144
Registration Number
NCT06723106
Locations
🇨🇦

DiIEX Recherche Sherbrooke, Inc, Sherbrooke, Quebec, Canada

🇯🇵

Okayama University Hospital, Okayama, Japan

🇦🇺

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

and more 51 locations

Phase Ib Open Label Basket Trial of RAY121 to Inhibit Classical Complement Pathway in Immunological Diseases (RAINBOW Trial)

Phase 1
Recruiting
Conditions
Dermatomyositis
Immune Thrombocytopenia
Behçet’s Syndrome
Antiphospholipid syndrome
Immune-mediated necrotizing myopathy
Bullous pemphigoid
Interventions
First Posted Date
2024-07-09
Last Posted Date
2025-04-14
Lead Sponsor
Chugai Pharmaceutical Co. Ltd.
Target Recruit Count
87
Registration Number
2023-507692-21-00
Locations
🇷🇴

Institute Of Oncology Prof. Dr. Ion Chiricuta Cluj-Napoca, Cluj-Napoca, Romania

🇷🇴

Centrul Medical Monza S.R.L., Bucharest, Romania

🇪🇸

Clinica Universidad De Navarra, Madrid, Spain

and more 33 locations

A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors

Phase 1
Recruiting
Conditions
Solid Tumor
Interventions
First Posted Date
2023-06-18
Last Posted Date
2025-03-25
Lead Sponsor
Chugai Pharmaceutical
Target Recruit Count
219
Registration Number
NCT05907980
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

NEXT Oncology, Fairfax, Virginia, United States

🇯🇵

National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan

and more 1 locations
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News

Chugai and Gero Form $250M Partnership to Develop AI-Driven Antibody Therapies for Age-Related Diseases

Chugai Pharmaceutical and Singapore-based Gero have entered into a joint research and license agreement to develop novel antibody therapies targeting age-related diseases using AI-driven drug discovery.

Roche Announces Leadership Changes as Head of Pharma R&D Hans Clevers Retires

Johannes (Hans) Clevers, Head of Roche Pharma Research and Early Development (pRED), will retire at the end of August 2025 after accelerating several potentially transformational medicines into final development phases.

NEC and Chugai Pharmaceutical Develop AI System to Accelerate Cancer Drug Combination Discovery

NEC Corporation and Chugai Pharmaceutical have successfully tested an AI system that can predict effective cancer drug combinations, potentially reducing prediction time by approximately 50% compared to conventional methods.

Chugai Pharmaceutical Eyes Combination Therapy to Set New Standard for Obesity Treatment

Chugai Pharmaceutical, the Japanese biotech behind Eli Lilly's oral obesity drug orforglipron, plans to combine it with its anti-muscle wasting drug GYM329 to create a new standard of care for weight loss patients.

Nemluvio Shows Sustained Long-Term Efficacy in Atopic Dermatitis with Two-Year Extension Data

New two-year data from the ARCADIA long-term extension study demonstrate that Nemluvio (nemolizumab) maintains sustained and increased improvements in itch, skin lesions, sleep, and quality of life in patients with moderate-to-severe atopic dermatitis.

Tecentriq and Avastin Combined with TACE Shows Significant Benefit in Unresectable Liver Cancer Trial

The Phase III TALENTACE study demonstrated statistically significant improvement in TACE-progression-free survival for patients with unresectable hepatocellular carcinoma treated with Tecentriq, Avastin, and on-demand TACE.

Rani Therapeutics and Chugai Pharmaceutical Partner to Advance Oral Antibody Delivery Technology

Rani Therapeutics has entered a research agreement with Chugai Pharmaceutical to evaluate the application of its RaniPill® oral delivery technology for Chugai's antibodies against undisclosed targets.

Taiwan Approves Chugai's PiaSky as First Subcutaneous Treatment for Paroxysmal Nocturnal Hemoglobinuria

Taiwan FDA has granted orphan drug approval for PiaSky, making it the first subcutaneous treatment for paroxysmal nocturnal hemoglobinuria (PNH) available in Taiwan for patients 13 years and older.

Chugai Seeks Approval for Tecentriq to Treat Rare Thymic Carcinoma in Japan

Chugai Pharmaceutical has filed for regulatory approval to use Tecentriq (atezolizumab) in combination with carboplatin and paclitaxel for treating thymic carcinoma in Japan, with the application granted priority review status.

Chugai's Vabysmo Becomes First Approved Treatment for Angioid Streaks in Japan

Chugai Pharmaceutical has received Japanese regulatory approval for Vabysmo as the first-ever treatment for choroidal neovascularization associated with angioid streaks, a rare eye disease that can lead to vision loss.

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