Reliability, Validity and Clinical Utility of a Robotic Assessment for Proprioception
- Conditions
- Multiple SclerosisNeurological Diseases or ConditionsSensory DisordersStroke
- Interventions
- Other: Robotic assessment of finger proprioception
- Registration Number
- NCT03619642
- Lead Sponsor
- Hasselt University
- Brief Summary
The aim of this case-controlled observational cross-sectional study is to investigate the test-retest reliability, validity and clinical utility of a rapid robotic assessment of finger proprioception using a passive gauge position matching tasks in MS and stroke subjects.
Session 1 Informed consent Descriptive measures Session 2 Clinical testing Robotic assessment (3x) Session 3 Clinical testing Robotic assessment (3x)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion criteria MS subjects
- Age > 18 years
- Diagnosis of MS (McDonald criteria)
- No relapse or relapse-related treatment within the last 3 months prior to the study
Inclusion criteria Stroke subjects
- Age > 18 years
- Diagnosis of stroke (ischemic or hemorrhagic),
- Between 2 weeks and 12 months post-stroke
- Complete paralysis of both upper limbs
- Unable to detect any passive movement in hand and fingers
- Unable to place the hand in the robotic devices without any discomfort or pain
- Marked or severe intention tremor (Fahn's tremor rating scale on finger-to-nose test > 3)
- Marked or severe spasticity for finger and elbow flexors or shoulder adductors (Modified Asworth scale >3)
- Other medical conditions interfering with the hand function (peripheral nerve lesion, orthopedic or rheumatoid impairment, pain, edema)
- Severe cognitive or visual deficits interfering with testing and training (e.g. Aphasia, neglect, ...)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description stroke patients Robotic assessment of finger proprioception 25 stroke patients Persons are tested on proprioception of the interphalangeal joints of teh fingers by means of a robotic device. healthy controls Robotic assessment of finger proprioception 50 healthy controls Persons are tested on proprioception of the interphalangeal joints of teh fingers by means of a robotic device. persons with Multiple Sclerosis (MS) Robotic assessment of finger proprioception 25 persons with MS Persons are tested on proprioception of the interphalangeal joints of teh fingers by means of a robotic device.
- Primary Outcome Measures
Name Time Method Error day 3 The extracted parameter is measured by the robotic device. The MCP angular position measured by the robot and the angle reported on the touchscreen by the subject.
- Secondary Outcome Measures
Name Time Method Semmens-Weinstein monofilaments day 3 Tactile sensitivity in the fingers (Semmens-Weinstein monofilaments)
sex day 1 man/female
Age day 1 age
medication use day 1 medication use at time of study
the modified Ashworth scale day 1 Spasticity of the upper limb will be evaluated with the modified Ashworth scale
Edinburgh Handedness Inventory day 1 Hand Dominance evaluated with Edinburgh Handedness Inventory
Nine Hole Peg test day 1 manual dexterity test
Box and block test day 1 gross and fine upper limb test
Manual Ability Measure-36 (questionnaire) day 1 Patient reported measure for upper limb use in daily life activities
Symbol digit modalities test day 1 Cognitive function (Symbol digit modalities test)
25 foot walk test day 1 Gait velocity test
Rydel Seiffer Tuning fork day 3 Vibration in the upper limb (Rydel Seiffer Tuning fork)
The Erasmus MC modification of the Nottingham Sensory Assessment (EmNSA) day 3 Sensory function test
The System Usability Scale (SUS) day 3 questionnaire
Trial Locations
- Locations (2)
Jessa Ziekenhuis
🇧🇪Hasselt, Belgium
Revalidatie & MS Centrum Overpelt
🇧🇪Overpelt, Belgium