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Clinical study of Shugan Hewei granule in the treatment of refractory gastroesophageal reflux disease with qi stagnation and phlegm obstructio

Phase 1
Conditions
gastroesophageal reflux disease
Registration Number
ITMCTR2000003657
Lead Sponsor
Yueyang Hospital of Integrated Traditioanl Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

A. It was in accordance with the diagnostic criteria of qi stagnation and phlegm resistance type of acid vomiting (gastroesophageal reflux disease).
B. Before this study, patients with gastroesophageal reflux disease (GERD) were treated with standard dose PPI for four weeks or more.
C. The age is 18-70 years old, with no gender limit.

Exclusion Criteria

A. Patients with one of the following diseases: peptic ulcer, history of gastroesophageal and duodenal surgery, Zhuo AI syndrome, primary esophageal motility disorders (such as achalasia, scleroderma, primary esophageal spasm), malignant lesions of upper gastrointestinal tract, coronary heart disease, diabetes, drug-induced esophagitis, and psychotic patients.
B. Pregnant women and allergic constitution patients.
C. The patient himself is the researcher directly involved in this clinical study.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Observation of clinical symptoms;electrocardiogram;Quality of life assessment;Electronic gastroscope;
Secondary Outcome Measures
NameTimeMethod
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