Estimation of Perioperative Atelectasis

Completed

• Conditions: Oxygenation; Atelectasis

• Registration Number: NCT03352336
• Lead Sponsor: Region Västmanland

Brief Summary

This study will compare an oxygenation test based on arterial blood gas analysis with computed tomography for estimating the extent of atelectasis.

Detailed Description

Computed tomography of the lungs is the gold standard for investigating the extent of atelectasis, which is common in the perioperative setting. Atelectasis increase the risk of postoperative pulmonary complications and result in pulmonary shunt, which is one of the two major causes of impaired oxygenation. The other cause is admixture of venous blood from poorly ventilated regions of the lungs. The investigators have developed an oxygenation test utilizing arterial blood gas analysis at different inspired fractions of oxygen, which may be used to distinguish between these two causes. This observational study aims to establish the agreement between computed tomography and the oxygenation test for estimating the extent of atelectasis.

Study Timeline

• Study First Submitted: 2017-11-19
• Study First Submitted QC: 2017-11-21
• Study First Posted: 2017-11-24
• Study Start: 2017-12-04
• Primary Completion: 2018-08-28
• Study Completion: 2018-08-28
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-11
• Last Update Posted: 2018-10-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• American Society of Anesthesiology (ASA) class I-II.
• Non-abdominal day case surgery under general anesthesia.
• Patients enrolled in study registered in ClinicalTrials with NCT ID.

Exclusion Criteria

• Arterial oxygen saturation (SpO2) <90 % with 40% Venturi mask.
• Unstable postoperative condition needing immediate treatment.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Atelectasis area	30 min after emergence from anesthesia	Atelectasis area as studied by computed tomography

Secondary Outcome Measures

Name	Time	Method
Pulmonary shunt estimated by a standardised oxygenation test	30 min after emergence from anesthesia	Pulmonary shunt estimated by a standardised oxygenation test using

Trial Locations

Locations (1)

Västmanlands sjukhus Köping; 🇸🇪 Köping, Västmanland, Sweden