Clinical profile of neonates admitted in NICU with sepsis : A cross sectional study

Parents of all the neonates were invited to participate in the study. The study population consisted of all neonates admitted with a history and clinical features suggestive of neonatal sepsis, and attendants who gave consent to participate were enrolled in the study. For all the patients who gave consent to participate and met the inclusion criteria, a detailed maternal medical and obstetric history was obtained. Information regarding gestation, including complications during pregnancy, gestational age at delivery, mode of delivery, and birth weight, was recorded. A detailed history of the neonates suggestive of neonatal sepsis was taken. A comprehensive general and systemic examination of the neonates was performed, and neonatal risk factors were identified.

Sepsis screen investigations were conducted, which included:

Complete Blood Count (CBC), Micro ESR, C-reactive protein (CRP), Blood culture and antibiotic sensitivity, Immature/Total neutrophil ratio, Urine culture sensitivity, CSF culture and sensitivity (for suspected cases of meningitis), Absolute neutrophil count

These investigations were used to identify indicators suggestive of neonatal sepsis.