Convalescent plasma for early Ebola virus disease in Sierra Leone

Phase 2

Completed

• Conditions: Early Ebola virus disease; Infections and Infestations

• Registration Number: ISRCTN13990511
• Lead Sponsor: niversity of Liverpool

Brief Summary

2018 Other publications in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947131/ article on feasibility of donor recruitment (added 01/08/2019) 2021 Other publications in https://pubmed.ncbi.nlm.nih.gov/33505020/ (added 17/05/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-04-27
• Study Completion: 2017-03-31
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

1. Persons of all ages and sex admitted to Ebola treatment units with confirmed Ebola virus disease
2. Health care workers who experience a safety incident as a result of the intervention
3. Survivors of Ebola virus disease who volunteer to donate plasma

Exclusion Criteria

1. Those for whom the intervention is contraindicated
2. Those who are unresponsive (per AVPU) just prior to intervention
3. Those for whom any intervention is considered futile

Study & Design

• Study Type: Interventional
• Study Design: Not specified