sing resting-state functional magnetic resonance imaging to investigate a central mechanism of contralateral acupuncture at Hand-Yangming in patients with cerebral ischemic stroke
- Conditions
- Cerebral ischemia stroke
- Registration Number
- ITMCTR2100004539
- Lead Sponsor
- Hospital of Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Corresponding to the diagnostic standards of cerebral ischemic stroke(Referring to the 2019 version cerebral vascular disease diagnostic criteria) and diagnosed with CIS and confirmed by CT or MRI, occurred >= 2 weeks and <= 6 months previously, stable vital sign and consciousness without disorders of language;
(2) According to the OCSP clinical classification standard, it is partial anterior circulation infarction (PACI), and the lesion is mainly on the right basal ganglia and/or corona radiata;
(3) The initial onset, hemiplegia existed in one limb, NIHSS score >= 3 and < 10 or(and) the upper limbs function score of Brunnstrom stages recovery at the stage 1-5;
(4) Aged between 35 and 75 years;
(5) Informed consent signed by the patient or by the patient's relative;
(6) Patients who have better compliance and can complete the research.
(1) Course of disease > 6 months, or advanced acute stroke, or unstable vital sign;
(2) Persons with Wernicke's aphasia, severe cognitive impairment, mental illnesses or post-stroke depression.
(3) Patients with severe heart, lung, liver, and kidney diseases;
(4) Patients have pacemakers and metal implants in the body and underwent bypass operation or can't undergo MRI;
(5) Persons with skin disease and coagulation dysfunction;
(6) Pregnant women or women in puerperium;
(7) Patients who can't cooperate with treatment, observation and examination.
(8) Participants in other clinical tests at the same time.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method R-fMRI;
- Secondary Outcome Measures
Name Time Method Brunnstrom;NIH Stroke Scale scores;SS-QOL;Fugl-Meyer;MoCA;MBI;MMSE;