Resting State functional magnetic resonance imaging of human brain responses to nutrient shakes.

Completed

• Conditions: Feeding behavior; Response to feeding; 10003018

• Registration Number: NL-OMON43766
• Lead Sponsor: nilever

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Signed informed constent
Age between 18 and 25 years
Bodyweight of at least 70 kg
BMI between 20 and 23 kg/m2

Exclusion Criteria

-Diabetes or history of other disturbances of glucose metabolism (eg impaired glucose tolerance, hypoglycemia).
-Any genetic or psychiatric disease (e.g. fragile X syndrome, major depression) affecting brain
-Any significant chronic disease
-Any known food allergies or intolerances
-Renal or hepatic disease
-Recent weight changes or attempts to lose weight (> 3 kg weight gain or loss, within the last 3 months)
-Smoking (current or last 6 months)
-Alcohol consumption of more than 21 units per week or use of recreational drugs at present or in the last year
-Recent participation in other biomedical research projects (within the last 3 months), participation in 3 or more biomedical research projects in one year
-Contra-indication to MRI scanning

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in brain connectivity and activity, as measured by rsfMRI.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Psychophysical ratings of hunger, taste and sweetness</p><br>