Effect of Zingiber zerumbet pomade in treatment of knee arthrosis
- Conditions
- Osteoarthritis.Arthrosis, unspecified
- Registration Number
- IRCT20170428033670N1
- Lead Sponsor
- Immunology Research Center of Shahed University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Out-patients who suffer osteoarthritis based on clinical criteria of ACR
Those who need more than 2 grams of acetaminophen daily
Those who need to use other oral or intravenous analgesic
Sensitivity to study drugs
Patients with Secondary osteoarthritis caused by rheumatic diseases such as rheumatoid arthritis
Pregnancy
Joint Replacement
Concomitant use of glucosamine and chondrotin sulfate
Knee corticosteroid injection in the past 3 months
Oral or topical use of Corticosteroid in 14 past days
Other Articular corticosteroid injection in the past 1 months
Mussle corticosteroid injection in the past 1months
Skin Diseases in Knee
Radiculopathy and Neuropathy
Alcohol addicted, Drug Abuse
Patients with active Renal, Liver, and Peptic Ulcer Diseases
Age under 30 or over 80 years
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire.;Physical Function. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire.;Stiffness. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire.
- Secondary Outcome Measures
Name Time Method Interleukin 1. Timepoint: Before the intervention and the end of the fourth week after the start of the intervention. Method of measurement: Venous blood sample.;Interleukin 6. Timepoint: Before the intervention and the end of the fourth week after the start of the intervention. Method of measurement: Venous blood sample.