The Safety and Efficacy of 1064-nm Picosecond Laser With Microlens Array for Pore Tightening; a Pilot Study

Not Applicable

• Conditions: Enlarged Pores
• Interventions: Device: Fractional picosecond 1064 nm laser

• Registration Number: NCT04471948
• Lead Sponsor: Mahidol University

Brief Summary

The objective of this study is to evaluate the safety and efficacy of 1064-nm Picosecond laser 1064 With Microlens Array for Pore tightening.

Detailed Description

The Safety and Efficacy of Picosecond laser 1064 Nanometers With Microlens Array for Pore tightening; a Pilot Study Primary outcome : pore size Secondary outcome : side effect, patient satisfaction, global evaluation the patient recieved laser treament once a month for 3 months and then follow up after last treatment at 1, 3 ,6 month

Enlarged facial pores is one of the skin signs in photoaging. There are 3 major clinical causes of enlarged facial pores: highs sebum excretion, decreased elasticity around pores and increased hair follicle volume. Possible causative factors of enlarged facial pores include many exogenous and endogenous factors include genetic predisposition, seborrhea and chronic ultraviolet light exposure. Picosecond laser are new device which has been used in skin rejuvenation. The main mechanism of action is laser induced optical breakdown (LIOB).

Study Timeline

• Study Start: 2020-05-07
• Study First Submitted: 2020-07-09
• Study First Submitted QC: 2020-07-11
• Study First Posted: 2020-07-15
• Status Verified: 2021-03
• Primary Completion: 2021-03-07
• Study Completion: 2021-03-07
• Last Update Submitted: 2021-03-11
• Last Update Posted: 2021-03-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Both male and female age 25-40 years
• No underlying disease

Exclusion Criteria

• History of retinoid or other keratolytic drugs used within 6 months before enrolled
• History of keloid
• photosensitivity
• Immunocompromised host

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Fractional picosecond laser 1,064 nm laser	Fractional picosecond 1064 nm laser	1 arm The subjects with enlarged pores were treated with fractional picosecond laser 1,064 nm laser

Primary Outcome Measures

Name	Time	Method
Change in pore size by Antera 3D image	change from baseline in pore size at 6 months

Trial Locations

Locations (1)

Department of Dermatology, Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok, Thailand