A study to see the effect of two drugs, norepinephrine and mephentermine for maintenance of blood pressure during caesarean section.
Not Applicable
Completed
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2019/06/019652
- Lead Sponsor
- Dr PJ Shah
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 297
Inclusion Criteria
1. ASA Physical status â??Ð?Ð?
2. Singleton pregnancy
3. Term Pregnancy
4. Elective Cesarean Delivery
5. Weight 50-100kg
6. Height 140-180 cm
7. Age 18-35 years
Exclusion Criteria
1.Pre-existing or Pregnancy induced Hypertension
2.Known fetal abnormality
3.Cardiovascular or Cerebrovascular disease
4.Gestational Diabetes Mellitus
5.Renal Impairment
6.Allergy to Norepinephrine & Mephentermine
7. Medication- MAO Inhibitors or TCA
8.Intraoperative use of uterotonic other than oxytocin
9.Presence of mesenteric or peripheral vascular thrombosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maternal Systolic Blood PressureTimepoint: At every 2 minutes after administration of spinal anaesthesia till 20 minutes and every 5 minutes there after till completion of surgery.
- Secondary Outcome Measures
Name Time Method Maternal diastolic blood pressure,Maternal mean blood pressure,Maternal heart rate,Total dose of vasopressor required for correction of hypotension <br/ ><br>Timepoint: At every 2 minutes after administration of spinal anaesthesia till 20 minutes and every 5 minutes there after till completion of surgery.