Management of spinal induced hypotension in caesarean section using bolus doses of Norepinephrine or Phenylephrine
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/06/034490
- Lead Sponsor
- Andrea Nongsiej
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
1. Patients with ASA physical grade I or II
2. Patients willing to give written informed consent
Exclusion Criteria
1. History of allergy to local anaesthetic agent and/or drugs
2. Bleeding disorders like Von Willebrand disease, ITP, platelet count <50,000/micro litre, prothrombin time >14 seconds, INR >1.5, other obstetric omplications associated with coagulopathy (placental abruption, pre eclampsia)
3. Local site infection
4. Spinal deformity
5. Cardiac, respiratory diseases and kidney disorder, neurological deficit
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the number of intravenous bolus doses of norepinephrine or phenylephrine required to treat spinal hypotension <br/ ><br>Timepoint: The outcome will be assessed at baseline, 2 minutes, 4 minutes, 6 minutes, 8 minutes, 10 minutes, then every 5 minutes till the end of the surgery
- Secondary Outcome Measures
Name Time Method To compare the incidence of bradycardia, hypertension, nausea and vomiting in mother and foetal outcomes such as Apgar score and umbilical vein blood gases. <br/ ><br>Timepoint: The outcome will be assessed at baseline, 2 minutes, 4 minutes, 6 minutes, 8 minutes, 10 minutes, then every 5 minutes till the end of the surgery