Comparison of two drugs Norepinephrine and Phenylephrine used for the treatment of fall in blood pressure after spinal anaesthesia for Caeserean delivery of uncomplicated pregnancy
Phase 3
Completed
- Conditions
- Health Condition 1: O82- Encounter for cesarean delivery without indicationHealth Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2018/08/015364
- Lead Sponsor
- amrita institue of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 56
Inclusion Criteria
Elective CS under spinal anaesthesia,
Normal singleton pregnancy beyond 36 weeks gestation,
ASA physical status 1 or 2,
Weight 50-100 kg,
Height 150-180 cm.
Exclusion Criteria
Allergy or hypersensitivity to phenylephrine or norepinephrine,
Any hypertensive disorders of pregnancy,
Cardiovascular or cerebrovascular disease,
Fetal abnormalities.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare number of boluses of norepinephrine vs. phenylephrine required to maintain maternal blood pressure when used to treat post-spinal hypotension in patients undergoing caesarean section.Timepoint: end of surgery
- Secondary Outcome Measures
Name Time Method To compare the effects of these two drugs on incidence of bradycardia, hypertension, nausea& vomiting in mother and foetal outcomes such as APGAR score & umbilical vein blood gases.Timepoint: end of surgery