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Vasopressors and acidosis in neonates in caesarean section during spinal anaesthesia

Phase 4
Conditions
Health Condition 1: null- Patients with uncomplicated normal singleton term pregnancy scheduled for elective caesarean section under spinal anaesthesia.
Registration Number
CTRI/2018/03/012773
Lead Sponsor
Government Medical College and Hospital Chandigarh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

a)Patients belonging to American Society

of Anaesthesiologists I & II.

b)Age 18 â?? 35 years.

c)Patients with uncomplicated normal

singleton term pregnancy scheduled for

elective caesarean section under spinal

anaesthesia.

Exclusion Criteria

a)Patients with absolute / relative

contra-indications for spinal

anaesthesia.

b)Patient with pregnancy induced

hypertension.

c)Patients suffering from intercurrent

medical diseases (Cardiovascular,

Cerebrovascular or renal).

d)Patients with history of allergy to any

of the study drugs.

e)Patients having conditions such as

oligohydroamnios, intrauterine growth

restriction (IUGR) which can explain

pre-existing foetal hypoxemia or

neonatal acidemia.

f)Patients suffering from connective

tissue disorders which reduce blood

flow to the placenta such as systemic

lupus erythematosus.

g)Patient refusal to participate in

study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
mbilical arterial blood pHTimepoint: Immediately after delivery
Secondary Outcome Measures
NameTimeMethod
Apgar score; Umbilical vein blood pH; Maternal systolic and diastolic blood pressure; Mean arterial pressure; Maternal hypotension; Maternal heart rate; Reactive hypertension; Bolus of vasopressor; Side effects of drugTimepoint: From spinal injection to delivery after every one minute
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