A clinical trial to study the effects of two drugs,Phenylephrine and Norepinephrine in patients undergoing elective cesarean section to prevent and treat fall in blood pressure.
Not Applicable
Completed
- Registration Number
- CTRI/2021/07/035063
- Lead Sponsor
- Dr Megha Maheshwari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Women posted for elective cesarean section under spinal anaesthesia with singleton, term, uncomplicated pregnancy
2)Weight between 50 to 100kg
3)Height between 150 to 170cm
4)Women belonging to ASA physical status 2
Exclusion Criteria
1)Patient refusal
2)Patient who are contraindicated for spinal anaesthesia
3)Patient with obstetric complication like preexisting or pregnancy induced hypertension, cardiovascular disease, cerebrovascular disease and preexisting diabetes, gestational diabetes
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of maternal bradycardia (less than 55 bpm) between two vasopressors infusionTimepoint: Every 2 minutes after giving spinal anaesthesia till delivery of fetus (cord clamping)
- Secondary Outcome Measures
Name Time Method 1)To compare systolic arterial pressure between two groups <br/ ><br>2)To compare frequency of post spinal hypotension and reactive hypertension <br/ ><br>3)To compare umbilical artery and vein blood gases between two groups <br/ ><br> <br/ ><br>4)To compare incidence of fetal acidosis(umbilical artery blood pH less than 7.2) <br/ ><br>5)To compare Apgar score at 1 and 5 minutes <br/ ><br>6)To compare umbilical vein blood glucose level <br/ ><br>7)To compare maternal side effects like nausea,vomiting, dizziness,change in skin colorTimepoint: ..;To compare Apgar score at 1 and 5 minutes after delivery of babyTimepoint: 1 and 5 minutes after delivery