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Effects of Light and Exercise on Human Circadian Rhythms and Performance

Not Applicable
Completed
Conditions
Circadian Rhythm
Interventions
Behavioral: Light and exercise
Registration Number
NCT02747719
Lead Sponsor
Brigham and Women's Hospital
Brief Summary

Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels. The investigators propose to test the combined effects of these two countermeasures to determine whether adding exercise to light stimuli will further improve circadian phase resetting and alertness.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8
Inclusion Criteria
  • healthy by history, physical exam, laboratory studies of blood and urine, and psychological screening
  • moderate-intensity exercise for at least 150 minutes per week
Exclusion Criteria
  • color blind
  • no prescription medications, except hormonal birth control in females

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Light and exerciseLight and exerciseExposure to light with exercise
Primary Outcome Measures
NameTimeMethod
Circadian Phase8 days

Circadian Phase will be measured using the change in timing of the melatonin rhythm on different days of the protocol. Melatonin will be assayed in blood and/or saliva.

Secondary Outcome Measures
NameTimeMethod
Subjective alertness8 days

Subjective alertness will be measured using the change in values on standardized mood scales on different days of the protocol.

Trial Locations

Locations (1)

Brigham and Women's Hospital

🇺🇸

Boston, Massachusetts, United States

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