Effects of Light and Exercise on Human Circadian Rhythms and Performance
- Conditions
- Circadian Rhythm
- Interventions
- Behavioral: Light and exercise
- Registration Number
- NCT02747719
- Lead Sponsor
- Brigham and Women's Hospital
- Brief Summary
Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels. The investigators propose to test the combined effects of these two countermeasures to determine whether adding exercise to light stimuli will further improve circadian phase resetting and alertness.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 8
- healthy by history, physical exam, laboratory studies of blood and urine, and psychological screening
- moderate-intensity exercise for at least 150 minutes per week
- color blind
- no prescription medications, except hormonal birth control in females
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Light and exercise Light and exercise Exposure to light with exercise
- Primary Outcome Measures
Name Time Method Circadian Phase 8 days Circadian Phase will be measured using the change in timing of the melatonin rhythm on different days of the protocol. Melatonin will be assayed in blood and/or saliva.
- Secondary Outcome Measures
Name Time Method Subjective alertness 8 days Subjective alertness will be measured using the change in values on standardized mood scales on different days of the protocol.
Trial Locations
- Locations (1)
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States