NCT00750347已完成1 期
Evaluation of the Interaction of Rimonabant (Antagonist of CB1 Receptor) on the Analgesic Effect of Paracetamol in Intravenous Administration
University Hospital, Clermont-Ferrand4 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2008年9月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 4
- 主要终点
- Pain's threshold with electrical stimulation (Pain Matcher). Pain's threshold with mechanical stimulation (electronical Von Frey).
研究概览
简要总结
Evaluation of an possible inhibiting effect of Rimonabant on the analgesic effect of Paracetamol in healthy volunteers
详细描述
Double Blind, cross-over, randomized and controlled versus placebo, study in healthy volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
- •between 18 and 40 years old
- •written consent given
排除标准
- •Rimonabant or paracetamol hypersensibility
- •Excessive consumption of alcohol, tobacco, coffee, tea or toxicomania
- •Concomitant medication
- •Chronical diseases
结局指标
主要结局
Pain's threshold with electrical stimulation (Pain Matcher). Pain's threshold with mechanical stimulation (electronical Von Frey).
时间窗: during electrical stimulation
次要结局
- Plasmatic concentration of paracetamol or his metabolite with or without Rimonabant(with or without rimonabant)
研究者
研究点 (4)
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