The Significance of Vitamin D Storage in Adipose Tissue
- Registration Number
- NCT01728987
- Lead Sponsor
- University of Tromso
- Brief Summary
The study will examine the role of adipose tissue in vitamin D physiology, particularly its role as a depot. the study is randomized double blind and placebo controlled.
- Detailed Description
vitamin d versus placebo will be given for 12 months. Biopsies will be taken at baseline and every 6 month for 2 years. Blood samples will be collected every 6th month. the study will thus give information on storage during vitamin d supplementation as well as use of vitamin d fat stores after stopping vitamin D supplementation
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- healthy subjects
Exclusion Criteria
- hypercalcemia
- pregnancy
- women without safe contraception
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description cholecalciferol cholecalciferol vitamin d (cholecalciferol) will be given as a capsule of 20.000 Iu twice a week placebo placebo the placebo capsules are looking identical to the vitamin d capsules and contain medium chain triglycerides and arachis oil
- Primary Outcome Measures
Name Time Method vitamin D in adipose tissue biopsies 12 months
- Secondary Outcome Measures
Name Time Method rate of decline of 25ohd in serum 12 months
Trial Locations
- Locations (1)
University of Tromsø
🇳🇴Tromsø, Norway
University of Tromsø🇳🇴Tromsø, Norway